Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Trypsin Inhibitor, Soybean, High Activity
Trypsin Inhibitor, Soybean, High Activity, CAS 9035-81-8 is of the several protease inhibitors in soybeans. Inhibits trypsin in 1:1 stoichiometry.
MilliporeSigma™ Calbiochem™ Methotrexate
Inhibits thymidylate synthetase, is a nonselective de novo purine synthesis inhibitor, and has a significant toxicity profile including hepatotoxicity, pneumonitis, and bone marrow suppress
MilliporeSigma™ Calbiochem™ Erastin
A cell-permeable piperazinyl-quinazolinone compound that exhibits oncogene-selective lethality.
MilliporeSigma™ Calbiochem™ InSolution™ Y-27632 in DMSO
InSolution™ Y-27632 is a 10mm solution in DMSO. A highly potent, cell-permeable, reversible, and selective inhibitor of Rho-associated protein kinases (Ki = 140nM for p160ROCK).
MilliporeSigma™ Calbiochem™ Wnt Antagonist I, IWR-1-endo
Wnt Antagonist I, IWR-1-endo, is a cell-permeable inhibitor of TNKS1/PARP5a (IC50 = 131 nM) & TNKS2/PARP5b (IC50≥ 56 nM). Suppress Wnt-stimulated transcription activity (IC50 = 180 nM).
MilliporeSigma™ Calbiochem™ EHNA, Hydrochloride
The racemic mixture of a cell-permeable adenine derivative that acts as a PDE II-selective phosphodiesterase inhibitor and adenosine deaminase.
MilliporeSigma™ Calbiochem™ Furin Inhibitor I
Furin Inhibitor I, is a peptidyl chloromethylketone that binds to the catalytic site of furin and blocks its activity.
MilliporeSigma™ Calbiochem™ Forskolin, Coleus forskohlii in DMSO
The major cell-permeable diterpene isolated from the Indian plant Coleus forskohlii.
MilliporeSigma™ Calbiochem™ DPDPE
A potent agonist selective for δ opioid receptor (EC50
MilliporeSigma™ Calbiochem™ InSolution™ TGF-β RI Kinase Inhibitor II, RepSox
A cell-permeable, potent, selective, reversible, and ATP-competitive inhibitor of TGF-β type I receptor (ALK5; IC50 = 23 nM, 4nM and 18nM for ALK5 binding, ALK5 auto-phosphorylation, and TGF-β cellular assay in HepG2 cells, respectively)
MilliporeSigma™ Calbiochem™ Amiloride, Hydrochloride
An inhibitor of angiogenesis.
MilliporeSigma™ Calbiochem™ SU5402
SU5402, CAS 215543-92-3, is a cell-permeable, reversible, and ATP-competitive inhibitor of the tyrosine kinase activity of FGFR1 (IC50 = 10 to 20 μM in the presence of 1 mM ATP).
MilliporeSigma™ Calbiochem™ Suramin, Sodium Salt
A reversible and competitive inhibitor of protein tyrosine phosphatases.
MilliporeSigma™ Calbiochem™ 2,3 cis-Piperidine dicarboxylic acid
A non-specific antagonist of NMDA, AMPA and kainate ionotropic receptors and a partial agonist for NMDA receptors.
MilliporeSigma™ Calbiochem™ BMX-IN-1
A cell-permeable tricyclic quinoline-acrylamide compound that potently inhibits BMX and BTK kinase activity (IC50 = 8 and