Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ JAK Inhibitor I
JAK Inhibitor I, CAS 457081-03-7, is a potent, reversible, cell-permeable, and ATP-competitive inhibitor of JAK 1 (IC50 = 15 nM), JAK2 (IC50 = 1 nM), JAK3 (Ki = 5 nM) and Tyk2 (IC50 = 1 nM).
MilliporeSigma™ Calbiochem™ Histone Deacetylase Inhibitor II
The Histone Deacetylase Inhibitor II, also referenced under CAS 174664-65-4, controls the biological activity of Histone Deacetylase. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ CXCR4 Antagonist IV, TF14016
A 14-aa internally disulfide-bonded peptide that potently competes against SDF-1α/CXCL12 for CXCR4 binding (IC50
MilliporeSigma™ Calbiochem™ Wnt Agonist II, SKL2001
The Wnt Agonist II, SKL2001 controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ Sialyltransferase Inhibitor, 3Fax-Peracetyl Neu5Ac
The Sialyltransferase Inhibitor, 3Fax-Peracetyl Neu5Ac controls the biological activity of Sialyltransferase.
MilliporeSigma™ Calbiochem™ PD 168393
A potent, cell-permeable, irreversible, ATP-competitive and selective inhibitor of EGF receptor (EGFR) tyrosine kinase activity (IC50 = 700 pM).
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MilliporeSigma™ Calbiochem™ Hsp70 Activator, YM-1
A stable and soluble MKT-077 analog that acts an allosteric activator of heat-shock protein 70 (HSP70)
MilliporeSigma™ Calbiochem™ Cathepsin L Inhibitor, CAA0225
An epoxysuccinyl peptide highly selective for rat liver cathepsin L (IC50
MilliporeSigma™ Calbiochem™ Rac Inhibitor III, EHop-016
The Rac Inhibitor III, EHop-016 controls the biological activity of Rac. This small molecule/inhibitor is primarily used for Membrane applications.
MilliporeSigma™ Calbiochem™ TLR1/TLR2 Agonist II, CU-T12-9
A diphenyl substituted imidazole based compound that directly and selectively targets TLR1/2 and induces their dimerization and activates TLR1 and 2 signaling leading to NF-κB and AP-1 activation ( K D = 182 and 478 nM, respectively; EC50
MilliporeSigma™ Calbiochem™ Ras Superfamily GTPases GTP/GDP Binding Antagonist, CID 1067700
The Ras Superfamily GTPases GTP/GDP Binding Antagonist, CID 1067700 controls the biological activity of Rab7. This small molecule/inhibitor is primarily used for Membrane applications.
MilliporeSigma™ Calbiochem™ SHP1/2 PTPase Inhibitor, NSC-87877
The SHP1/2 PTPase Inhibitor, NSC-87877, also referenced under CAS 56932-43-5, controls the biological activity of SHP1/2 PTPase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ PKC Inhibitor, EGF-R Fragment 651-658, Myristoylated
The PKC Inhibitor, EGF-R Fragment 651-658, Myristoylated controls the biological activity of PKC. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ FTY720
A cell-permeable aminopropanediol immunosuppressive agent that displays lymphocyte sequestration properties
MilliporeSigma™ Calbiochem™ PD 153035
An extremely potent, cell-permeamble, reversible, ATP-competitive and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR; IC50 = 25 pM; K